回魂夜

Chinese scientists develop electrode coating to address signal loss and tissue adhesion problems in long-term brain-computer interface implantation_我的网站

一 |     

    Photo: VCG
Chinese researchers have developed a multifunctional electrode coating that addresses key challenges in long-term brain-computer interface (BCI) implantation, including signal loss and tissue adhesion, bringing BCI one step closer to clinical application, the Global Times learned from the research team behind the findings on Sunday. 
As an emerging field combining neuroscience and artificial intelligence (AI), BCI faces a major challenge of ensuring long-term compatibility between electrodes and brain tissue. Previous clinical trials showed that immune responses could cause implanted electrodes to retract after just three months, severely reducing signal quality and the number of available channels. 
This problem stems from chronic inflammation triggered by implants, which creates insulating scar tissue around electrodes and separates them from neurons. Irreversible adhesion between electrodes and brain tissue after long-term implantation also makes device removal risky, potentially causing brain injury during follow-up surgeries.
Experiments showed that flexible neural electrodes coated with this material could operate stably in the brain for more than 300 days and could be safely removed without causing damage. This means the universal coating technology can make electrodes not only operate stably over the long term but can also be safely removed and replaced after aging, paving the way for long-term BCI applications.
Developed by the research team led by Zhang Wei at the Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, associated with Beijing Tiantan Hospital, Shanghai Institute of Microsystem and Information Technology and NeuroXess, a high-tech life science company specializing in BCI technologies, the cationic alternating peptide electrode coating preserves electrode flexibility and conductivity, while offering antibacterial, anti-protein adsorption and immune-rejection-inhibiting functions. 
A 300-day animal study showed the coating's effectiveness. Bare electrodes experienced a sharp loss of recording capability after 90 days of implantation and could barely detect neuronal signals after 300 days. In contrast, coated electrodes maintained stable recording channels and consistently captured neural signals above 155 microvolts. 
In terms of neural modulation, after 300 days of implantation, conventional electrodes required a current of 100 microamps to induce weak limb responses, while coated electrodes triggered clear movements with only 2 microamps, improving modulation efficiency by 50 times. 
Notably, the removal tests highlighted a key advantage of the coating that electrodes no longer form irreversible bonds with brain tissue. In the experiments, the coated electrodes were removed intact, with minimal damage to the surrounding brain tissue, Zhang told the Global Times on Sunday.
。1月11日消息，近期，小米股价继续下跌，特别是1月10日，小米公司股价创下上市以来的新低。

二 | 1月9日，小米集团（01810.hk）以10.50港元开盘，较昨日收盘价下跌5.41%。随后，小米集团发出通知，表示雷军的控股股东自愿承诺在未来365天内不出售其直接或间接受益股，但控股股东可以将其持有的公司B股（“激励股”）捐赠给慈善机构，但不超过639596190股。出于慈善目的。此外，CFO Weekly还承诺，自公告之日起365天内，不会单独出售小米库存。1月10日，小米股价收于每股9.97港元，连续几天跌至上市以来的新低。与去年7月每股22.20港元的高点相比，小米股价下跌了55%以上，市值蒸发了近3000亿港元。面对小米股价下跌，雷军在1月10日红米会议后接受媒体采访时也谈到了这个问题。雷军说：我喜欢公司的长期价值，自愿锁定（小米库存）365天，这之后我们看到了小米CFO，也长期价值，自愿锁定（小米库存）。

三 | 我们没有邀请其他小米员工，因为（这是）我昨天早上做了一个临时决定，太晚了（邀请其他小米员工）。我认为，通过实际行动，我们对公司的长期价值持乐观态度，我相信小米具有卓越的价值观和优秀的商业模式。我们正在推动中国各行各业的变革。我相信，因为我们的出现改变了手机行业和许多行业，我们相信一家伟大的公司将逐步实现长期价值。根据2008年第三季度小米报告，小米智能手机总收入350亿元，同比增长36%。2018年10月26日，小米智能手机年出货量超过1亿台。要观看视频，请单击此处。

四 |

Current article:http://ykrv.ruandaimingyunsun.sbs/news/20260826_48898.ppt

Published on:20:42:11